高架O迷宮（Zero maze）是高架十字迷宮的改進(jìn)，其實(shí)驗(yàn)原理與高架十字迷宮一樣，是利用動(dòng)物對(duì)新異環(huán)境的探究特性和對(duì)高懸敞開臂的恐懼形成的矛盾沖突行為來觀察動(dòng)物的焦慮狀態(tài)，是分析動(dòng)物焦慮反應(yīng)的經(jīng)典實(shí)驗(yàn)之一。該設(shè)計(jì)包括一個(gè)圓形平臺(tái)，兩個(gè)相對(duì)封閉的和兩個(gè)開放的象限，省去了傳統(tǒng)高架十字迷宮中用來連接中央圈所花費(fèi)的時(shí)間，并允許不間斷的探測(cè)。
Gene&I 在十多年的研究與服務(wù)過程中，積累了豐富的經(jīng)驗(yàn)，并不斷改進(jìn)產(chǎn)品設(shè)計(jì)與用戶體驗(yàn)，積極探索行為學(xué)的新發(fā)展方向！
Gene&I提供的O迷宮分析系統(tǒng)，不僅僅可以分析動(dòng)物在開放臂和封閉臂的拜訪次數(shù)停留時(shí)間、運(yùn)動(dòng)路程、潛伏期等常規(guī)參數(shù)，還可以通過動(dòng)物身體的百分比，嚴(yán)格定義動(dòng)物是處于開放臂還是封閉臂。實(shí)現(xiàn)試驗(yàn)的精確測(cè)量。
相關(guān)產(chǎn)品
Reference
Nguyen L N, Ma D L, Shui G H, et al. Mfsd2a is a transporter for the essential omega-3 fatty acid docosahexaenoic acid[J]. Nature, 2014: 1-16.
Goffin D, Brodkin E S, Blendy J A, et al. Cellular origins of auditory eventrelated potential deficits in Rett syndrome[J]. Nature Neuroscience | Brief Communication, 2014, 17(6): 804-808.
Dimitrov E L, Tsuda M C, Cameron H A, et al. Anxiety- and Depression-Like Behavior and Impaired Neurogenesis Evoked by Peripheral Neuropathy Persist following Resolution of Prolonged Tactile Hypersensitivity[J]. The Journal of Neuroscience, 2014, 34(37): 12304-12312.
Zou Y, Corniola R, Leu D, et al. Extracellular superoxide dismutase is important for hippocampal neurogenesis and preservation of cognitive functions after irradiation[J]. PNAS, 2012, 109: 21522 - 21527.
Wang I-T J, Allen M, Goffin D, et al. Loss of CDKL5 disrupts kinome profile and event-related potentials leading to autistic-like phenotypes in mice[J]. PNAS, 2012, 109(52): 21516 – 21521.